Clomid is the medication Clomiphene citrate. It is a hormone used to induce ovulation, to correct irregular ovulation, to increase egg production and to correct a condition known as luteal phase deficiency. It is a hormone that tricks the pituitary gland into producing more of certain hormones called FSH and LH, which in turn stimulate the ovary. Clomid is typically taken in doses from 59 mg to 200 mg, and taken for 5-9 days.
Clomid is among the most inexpensive fertility drugs. It is easily taken (orally rather than by injection) and it is the first line drug used for ovulation induction in patients with PCOS and other ovulatory disorders. It has been used for patients with luteal phase defect. It can also be used to assess ovarian reserve (the likelihood that a woman’s ovaries can still produce viable eggs). Clomid is not useful for women whose ovaries have reached the end of their working life.
Twin pregnancies may occur in as many as 5% of the women who use Clomid. Triplet pregnancies are far more rare. Clomid has been used to induce ovulation for more that thirty years. There is not any evidence that it causes an increase in congenital abnormalities or birth defects in children. It is not associated with an increase in premature labor or in other complications of pregnancy.
Just as women’s bodies are so different from one another, their reactions to Clomid vary tremendously. Some women have virtually no side effects. Others do, but they are more frequently related to emotions. Side effects may include mood swings, hot flashes, breast tenderness, thinning of the uterine lining, nausea and vomiting, visual symptoms and abnormal uterine bleeding. Clomid can cause hostile fertile mucous and thins the uterine lining in over 30 percent of the women who use it. The hostile mucus kills sperm, and the thin uterine can prevent implantation or cause an early miscarriage.